- About this Journal ·
- Abstracting and Indexing ·
- Aims and Scope ·
- Annual Issues ·
- Article Processing Charges ·
- Author Guidelines ·
- Bibliographic Information ·
- Citations to this Journal ·
- Contact Information ·
- Editorial Board ·
- Editorial Workflow ·
- Free eTOC Alerts ·
- Publication Ethics ·
- Recently Accepted Articles ·
- Reviewers Acknowledgment ·
- Submit a Manuscript ·
- Subscription Information ·
- Table of Contents
BioMed Research International
Volume 2013 (2013), Article ID 108951, 6 pages
Immunomodulatory Effect of Continuous Venovenous Hemofiltration during Sepsis: Preliminary Data
1Medical Intensive Care Unit, Department of Surgical and Anesthesiological Sciences, University Federico II of Naples, 80129 Naples, Italy
2Department of Nephrology, University Federico II of Naples, 80129 Naples, Italy
Received 7 May 2013; Accepted 22 June 2013
Academic Editor: Tiziano Verri
Copyright © 2013 Giuseppe Servillo et al. This is an open access article distributed under the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.
- D. C. Angus, W. T. Linde-Zwirble, J. Lidicker, G. Clermont, J. Carcillo, and M. R. Pinsky, “Epidemiology of severe sepsis in the United States: analysis of incidence, outcome, and associated costs of care,” Critical Care Medicine, vol. 29, no. 7, pp. 1303–1310, 2001.
- R. Beale, K. Reinhart, F. M. Brunkhorst, et al., “Promoting global research excellence in severe sepsis (PROGRESS): lessons from an international sepsis study,” Infectio, vol. 37, no. 3, pp. 222–232, 2009.
- C. Alberti, C. Brun-Buisson, H. Burchardi et al., “Epidemiology of sepsis and infection in ICU patients from an international multicentre cohort study,” Intensive Care Medicine, vol. 28, no. 2, pp. 108–121, 2002.
- E. Silva, A. Pedro Mde, A. C. Sogayar, et al., “Brasilian sepsis epidemiological study (BASES study),” Critical Care Medicine, vol. 8, no. 4, pp. R251–R260, 2004.
- M. R. Pinsky, J.-L. Vincent, J. Deviere, M. Alegre, R. J. Kahn, and E. Dupont, “Serum cytokine levels in human septic shock; Relation to multiple-system organ failure and mortality,” Chest, vol. 103, no. 2, pp. 565–575, 1993.
- R. C. Bone, C. J. Grodzin, and R. A. Balk, “Sepsis: a new hypothesis for pathogenesis of the disease process,” Chest, vol. 112, no. 1, pp. 235–243, 1997.
- C. Ronco, M. Bonello, V. Bordoni et al., “Extracorporeal therapies in non-renal disease: treatment of sepsis and the peak concentration hypothesis,” Blood Purification, vol. 22, no. 1, pp. 164–174, 2004.
- A. F. Grootendorst, “The potential role of hemofiltration in the treatment of patients with septic shock and multiple organ dysfunction syndrome,” Advances in Renal Replacement Therapy, vol. 1, no. 2, pp. 176–184, 1994.
- L. Cole, R. Bellomo, G. Hart et al., “A phase II randomized, controlled trial of continuous hemofiltration in sepsis,” Critical Care Medicine, vol. 30, no. 1, pp. 100–106, 2002.
- C. Ronco, R. Bellomo, P. Homel et al., “Effects of different doses in continuous veno-venous haemofiltration on outcomes of acute renal failure: a prospective randomised trial,” The Lancet, vol. 355, no. 9223, pp. 26–30, 2000.
- R. P. Dellinger, J. M. Carlet, H. Masur, et al., “Surviving Sepsis Campaign guidelines for management of severe sepsis and septic shock,” Intensive Care Medicine, vol. 34, pp. 17–60, 2008.
- W. Ertel, J.-P. Kremer, J. Kenney et al., “Downregulation of proinflammatory cytokine release in whole blood from septic patients,” Blood, vol. 85, no. 5, pp. 1341–1347, 1995.
- J.-M. Cavaillon, C. Munoz, C. Fitting, B. Misset, and J. Carlet, “Circulating cytokines: the tip of the iceberg?” Circulatory Shock, vol. 38, no. 2, pp. 145–152, 1992.
- R. P. Dellinger, J. M. Carlet, and H. Masur, “Surviving sepsis campaign guidelines for management of severe sepsis and septic shock,” Critical Care Medicine, vol. 32, no. 10, pp. 858–873, 2004.
- P. G. H. Metnitz, R. P. Moreno, E. Almeida et al., “SAPS 3-From evaluation of the patient to evaluation of the intensive care unit. Part 1: objectives, methods and cohort description,” Intensive Care Medicine, vol. 31, no. 10, pp. 1336–1344, 2005.
- R. P. Moreno, P. G. H. Metnitz, E. Almeida et al., “SAPS 3 - From evaluation of the patient to evaluation of the intensive care unit. Part 2: development of a prognostic model for hospital mortality at ICU admission,” Intensive Care Medicine, vol. 31, no. 10, pp. 1345–1355, 2005.
- J.-L. Vincent, R. Moreno, J. Takala et al., “The SOFA (Sepsis-related Organ Failure Assessment) score to describe organ dysfunction/failure,” Intensive Care Medicine, vol. 22, no. 7, pp. 707–710, 1996.
- B. Memoli, C. Libetta, T. Rampino et al., “Hemodialysis related induction of interleukin-6 production by peripheral blood mononuclear cells,” Kidney International, vol. 42, no. 2, pp. 320–326, 1992.
- R. Bellomo, P. Tipping, and N. Boyce, “Continuous veno-venous hemofiltration with dialysis removes cytokines from the circulation of septic patients,” Critical Care Medicine, vol. 21, no. 4, pp. 522–526, 1993.
- P. M. Honoré, O. Joannes-Boyau, and B. Gressens, “Blood and plasma treatments: the rationale of high-volume hemofiltration,” Contributions to Nephrology, vol. 156, pp. 387–395, 2007.
- A. Sander, W. Armbruster, B. Sander, A. E. Daul, R. Lange, and J. Peters, “Hemofiltration increases IL-6 clearance in early systemic inflammatory response syndrome but does not alter IL-6 and TNFα plasma concentrations,” Intensive Care Medicine, vol. 23, no. 8, pp. 878–884, 1997.
- C. Ronco, C. Tetta, F. Mariano et al., “Interpreting the mechanisms of continuous renal replacement therapy in sepsis: the peak concentration hypothesis,” Artificial Organs, vol. 27, no. 9, pp. 792–801, 2003.
- C. Horner, S. Schuster, J. Plachy, et al., “Hemofitration and immune response in severe sepsis,” Journal of Surgical Research, vol. 142, pp. 59–65, 2007.
- P. Toft, V. Brix-Christensen, J. Baech, et al., “Effect of hemofiltration and sepsis on chemotaxis of granulacyties and release of IL-8 and IL-10,” Acta Anaesthesiologica Scandinavica, vol. 46, no. 2, pp. 138–144, 2002.
- A. S. De Vriese, F. A. Colardyn, J. J. Philippé, R. C. Vanholder, J. H. De Sutter, and N. H. Lameire, “Cytokine removal during continuous hemofiltration in septic patients,” Journal of the American Society of Nephrology, vol. 10, no. 4, pp. 846–853, 1999.