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BioMed Research International
Volume 2013 (2013), Article ID 137985, 11 pages
http://dx.doi.org/10.1155/2013/137985
Review Article

Materials and Manufacturing Technologies Available for Production of a Pediatric Bioabsorbable Stent

Mattel Children’s Hospital, University of California, Los Angeles, CA 90095, USA

Received 23 May 2013; Accepted 6 August 2013

Academic Editor: Florence Siepmann

Copyright © 2013 Ryan D. Alexy and Daniel S. Levi. This is an open access article distributed under the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.

Abstract

Transcatheter treatment of children with congenital heart disease such as coarctation of the aorta and pulmonary artery stenosis currently involves the use of metal stents. While these provide good short term results, there are long term complications with their use. Children outgrow metal stents, obligating them to future transcatheter dilations and eventual surgical removal. A bioabsorbable stent, or a stent that goes away with time, would solve this problem. Bioabsorbable stents are being developed for use in coronary arteries, however these are too small for use in pediatric congenital heart disease. A bioabsorbable stent for use in pediatric congenital heart disease needs to be low profile, expandable to a diameter 8 mm, provide sufficient radial strength, and absorb quickly enough to allow vessel growth. Development of absorbable coronary stents has led to a great understanding of the available production techniques and materials such as bioabsorbable polymers and biocorrodable metals. Children with congenital heart disease will hopefully soon benefit from the current generation of bioabsorbable and biocorrodable materials and devices.