Research Article
Association Study of Single Nucleotide Polymorphisms in XRCC1 Gene with Risk of Hepatocellular Carcinoma in Chinese Han Population
Table 1
Clinical characteristics of hepatocellular carcinoma (HCC) cases and controls.
| Characteristics | Cases () | % | Controls () | % | value | value |
| Number | 651 | | 663 | | | | Gender () | | | | | 0.6900 | 0.4062 | Male | 389 | 59.75 | 411 | 61.99 | | | Female | 262 | 40.25 | 252 | 38.01 | | | Age (years) | | | | | | | Mean ± SD | | | 2.8181 | 0.0932 | <55 | 365 | 56.07 | 402 | 60.63 | | | ≥55 | 286 | 43.93 | 261 | 39.37 | | | Alcohol drinking | | | | | 2.3325 | 0.1267 | Yes | 332 | 51.00 | 366 | 55.20 | | | No | 319 | 49.00 | 297 | 44.80 | | | Tobacco smoking | | | | | 0.8282 | 0.3628 | Yes | 349 | 53.61 | 372 | 56.11 | | | No | 302 | 46.39 | 291 | 43.89 | | | Hypertension () | | | | | 0.1742 | 0.6764 | Yes | 115 | 17.67 | 123 | 18.55 | | | No | 536 | 82.33 | 540 | 81.45 | | | Diabetes mellitus () | | | | | 1.0300 | 0.3102 | Yes | 121 | 18.59 | 138 | 20.81 | | | No | 530 | 81.41 | 525 | 79.19 | | | Family history of HCC () | | | | | | | Yes | 48 | 7.37 | — | | | | No | 603 | 92.63 | — | | | | Serum a-FP levels | | | | | | | <400 ng/mL | 206 | 31.64 | — | | | | >400 ng/mL | 445 | 68.36 | — | | | | HBV serological markers () | | | | | | | HBs Ag (+) | 131 | 20.12 | — | | | | HBs Ag (−) | 520 | 79.88 | — | | | |
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