Research Article

Gamma Knife Surgery as Monotherapy with Clinically Relevant Doses Prolongs Survival in a Human GBM Xenograft Model

Figure 2

GKS prolongs survival in nude rats harboring GBM xenografts. Shown are the treatment groups as indicated for the experiment using pA (a–d) and pB (e) and (f) GBM xenografts. Treated rats (both 12 and 18 Gy collectively) versus controls from the time of implantation, (a) and from the time of treatment (b). Comparison of the individual treatment groups from the time of implantation (c) and from the time of treatment (d). Survival from the time of tumor (pB) implantation (e) and from the time of treatment (f).
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(a)
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(b)
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(c)
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(d)
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(e)
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(f)