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BioMed Research International
Volume 2013 (2013), Article ID 139813, 8 pages
http://dx.doi.org/10.1155/2013/139813
Research Article

Factors Influencing Women's Decision to Participate or Not in a Surgical Randomised Controlled Trial for Surgical Treatment of Female Stress Urinary Incontinence

1Division of Applied Health Sciences, University of Aberdeen, 2nd Floor, Aberdeen Maternity Hospital, Foresterhill, Aberdeen AB25 2ZD, UK
2Division of Applied Health Sciences, University of Aberdeen, Academic Urology Unit, 2nd Floor Health Sciences Building, Foresterhill, Aberdeen AB25 2ZD, UK

Received 29 April 2013; Accepted 29 July 2013

Academic Editor: Charnita M. Zeigler-Johnson

Copyright © 2013 Alyaa Mostafa et al. This is an open access article distributed under the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.

Abstract

The study aims to explore the potentially influential factors affecting women's decision to accept/decline participation in surgical randomised trial using a novel acceptance/refusal questionnaire (ARQ). All women who were eligible to participate in SIMS-RCT were asked to complete the relevant section (acceptance/refusal) of the ARQ. Women reported its degree of relevance for their decision on a six-point Likert scale (0 = highly irrelevant, 5 = highly relevant). 135 (98%) and 31 (70%) women completed the acceptance and refusal sections of the ARQ, respectively. The most influencing factor in women’s acceptance was the anticipation of “potential personal benefit”; percentage of relevance (POR) was 91.9%, followed by interest in helping others by “supporting innovative medical research”; POR was 87.7%. Most influencing factor in refusal for participation was “do not have time for follow-up”; POR was 56.8%, followed by “do not like the concept of randomisation”; POR was 54.4%. In conclusion, this study identifies the most influential factors relevant to women decision-making whether or not to participate in RCTs assessing surgical interventions for female stress urinary incontinence (SUI). A number of factors leading to refusal of participation are potentially correctable leading to better recruitment rates in future RCTs.