Pre- and Postsynaptic Dopamine SPECT in Idiopathic Parkinsonian Diseases: A Follow-Up Study

Table 1

The number of SPECTs in patients and HC, per SPECT timepoint.

	SPECT year	PD		APD		HC
		DAT	IBZM	DAT	IBZM	DAT	IBZM
Number of individuals (m/f)	0	29 (18/11)	29 (18/11)	20 (11/9)	18 (11/7)	14* (6/8)	14* (6/8)
	1	29 (18/11)	29 (18/11)	20 (13/7)	18 (13/5)	0	0
	3	22 (15/7)	17 (11/6)	10 (7/3)	10 (7/3)	16 (7/9)	16 (7/9)
		Mean ± SD	Mean ± SD	Mean ± SD	Mean ± SD	Mean ± SD	Mean ± SD
Age at first symptom		72.9±4.2	72.9±4.2	72.6±8.8	72.2±7.4
Age at SPECT	0	74.4±4.2	74.5±4.2	74.3±9.2	73.8±9.1	71.5±4.5	71.8±4.7
	1	75.5±4.2	75.5±4.2	75.1±5.1	74.9±5.2
	3	77.3±4.0	77.8±3.3	76.8±4.4	75.6±4.0	74.3±4.6	74.3±4.5

∗Two HCs were scanned on another camera at baseline SPECT: single photon emission computed tomography; DAT: dopamine transporter imaging with 123I-FP-Cit; IBZM: D2/D3 dopamine receptor imaging with 123I-IBZM; APD: atypical parkinsonian disease; PD: Parkinson’s Disease; HC: healthy controls; SD: 1 standard deviation.