Table 7: Yearly change (%) in uptake between baseline and 1-year followup: DAT and IBZM ratios.

N Mean95% CIMann-Whitney U test
HC versus PDHC versus MSAHC versus PSPPD versus MSAPD versus PSPMSA versus
PSP
P P P P P P

Contralateral
Caudate DAT
  PD 27−8.0−11.6–−4.50.005ns0.0060.013ns0.017
  MSA45.3−4.8–15.4
  PSP8−11.8−21.0–−2.7
  HC*14−0.5−2.2–1.3
Putamen DAT
  PD 27−6.5−10.8–−2.2nsns0.006nsnsns
  MSA4−3.3−14.4–7.8
  PSP8−13.9−23.0–−4.7
  HC*13−1.0−2.9–0.8
Striate DAT
  PD 27−7.2−10.6–−3.90.006ns0.004nsns0.042
  MSA40.8−10.4–11.9
  PSP8−12.8−21.6–−4.0
  HC*14−0.7−2.4–0.9
Ipsilateral
Caudate DAT
  PD 27−7.7−12.1–−3.40.045ns0.0060.045nsns
  MSA44.3−12.3–21.0
  PSP8−11.9−24.8–1.1
  HC*14−0.5−2.2–1.3
Putamen DAT
  PD 27−8.5−12.0–−4.90.006ns0.005ns(0.054)ns
  MSA4−8.2−28.0–11.5
  PSP8−13.4−26.9–0.1
  HC*13−1.0−2.9–0.8
Striate DAT
  PD 27−8.3−11.7–−5.00.002ns0.004nsnsns
  MSA4−1.9−19.2–15.4
  PSP8−12.8−25.5–0.0
  HC*14−0.7−2.4–0.9

Mean
Striate IBZM
  PD 29−3.1−6.2–0.0nsnsnsnsnsns
  MSA5−4.7−8.7–−0.7
  PSP8−8.3−19.8–3.3
  HC*14−2.1−3.5–−0.8

HC: average yearly change calculated between baseline and the 3-year follow-up SPECT.
Patients with same laterality as baseline.