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BioMed Research International
Volume 2013 (2013), Article ID 143742, 9 pages
Lithium Chloride Enhances Cathepsin H Expression and BMP-4 Degradation in C3H10T1/2 Cells
Department of Orthopaedic Surgery, Tohoku University School of Medicine, 1-1 Seiryo-machi, Aoba-ku, Sendai 980-8574, Japan
Received 10 July 2013; Accepted 26 September 2013
Academic Editor: Sue-Hwa Lin
Copyright © 2013 Koshi N. Kishimoto and Eiji Itoi. This is an open access article distributed under the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.
- A. H. Reddi, “Morphogenesis and tissue engineering of bone and cartilage: inductive signals, stem cells, and biomimetic biomaterials,” Tissue Engineering, vol. 6, no. 4, pp. 351–359, 2000.
- E. Kolpakova and B. R. Olsen, “Wnt/β-catenin—a canonical tale of cell-fate choice in the vertebrate skeleton,” Developmental Cell, vol. 8, no. 5, pp. 626–627, 2005.
- T. F. Day, X. Guo, L. Garrett-Beal, and Y. Yang, “Wnt/β-catenin signaling in mesenchymal progenitors controls osteoblast and chondrocyte differentiation during vertebrate skeletogenesis,” Developmental Cell, vol. 8, no. 5, pp. 739–750, 2005.
- T. P. Hill, D. Später, M. M. Taketo, W. Birchmeier, and C. Hartmann, “Canonical Wnt/β-catenin signaling prevents osteoblasts from differentiating into chondrocytes,” Developmental Cell, vol. 8, no. 5, pp. 727–738, 2005.
- K. N. Kishimoto, Y. Y. Watanabe, H. H. Nakamura, and S. S. Kokubun, “Ectopic bone formation by electroporatic transfer of bone morphogenetic protein-4 gene,” Bone, vol. 31, no. 2, pp. 340–347, 2002.
- K. N. Kishimoto and Y. Watanabe, “Bone formation by BMP gene transfection,” in Electroporation and Sonoporation in Developmental Biology, H. Nakamura, Ed., pp. 263–270, Springer, Berlin, Germany, 2009.
- P. S. Klein and D. A. Melton, “A molecular mechanism for the effect of lithium on development,” Proceedings of the National Academy of Sciences of the United States of America, vol. 93, no. 16, pp. 8455–8459, 1996.
- V. Turk, V. Stoka, O. Vasiljeva et al., “Cysteine cathepsins: from structure, function and regulation to new frontiers,” Biochimica et Biophysica Acta, vol. 1824, no. 1, pp. 68–88, 2012.
- A. G. Costa, N. E. Cusano, B. C. Silva, S. Cremers, and J. P. Bilezikian, “Cathepsin K: its skeletal actions and role as a therapeutic target in osteoporosis,” Nature Reviews Rheumatology, vol. 7, no. 8, pp. 447–456, 2011.
- D. Kuester, H. Lippert, A. Roessner, and S. Krueger, “The cathepsin family and their role in colorectal cancer,” Pathology Research and Practice, vol. 204, no. 7, pp. 491–500, 2008.
- S. Sulpizio, N. Franceschini, A. Piattelli, P. di Sebastiano, P. Innocenti, and F. Selvaggi, “Cathepsins and pancreatic cancer: the 2012 update,” Pancreatology, vol. 12, pp. 395–401, 2012.
- Z. Jevnikar, M. Rojnik, P. Jamnik, B. Doljak, U. P. Fonovic, and J. Kos, “Cathepsin H mediates the processing of talin and regulates migration of prostate cancer cells,” Journal of Biological Chemistry, vol. 288, pp. 2201–2209, 2013.
- M. Sivaparvathi, R. Sawaya, Z. L. Gokaslan, S. K. Chintala, and J. S. Rao, “Expression and the role of cathepsin H in human glioma progression and invasion,” Cancer Letters, vol. 104, no. 1, pp. 121–126, 1996.
- E. Frohlich, B. Schlagenhauff, M. Mohrle, E. Weber, C. Klessen, and G. Rassner, “Activity, expression, and transcription rate of the cathepsins B, D, H, and L in cutaneous malignant melanoma,” Cancer, vol. 91, pp. 972–982, 2001.
- T. Ueno, S. Linder, C.-L. Na, W. R. Rice, J. Johansson, and T. E. Weaver, “Processing of pulmonary surfactant protein B by napsin and cathepsin H,” Journal of Biological Chemistry, vol. 279, no. 16, pp. 16178–16184, 2004.
- J. Lü, J. Qian, D. Keppler, and W. V. Cardoso, “Cathespin H is an Fgf10 target involved in Bmp4 degradation during lung branching morphogenesis,” Journal of Biological Chemistry, vol. 282, no. 30, pp. 22176–22184, 2007.
- C. M. Jones, K. M. Lyons, and B. L. M. Hogan, “Involvement of Bone Morphogenetic Protein-4 (BMP-4) and Vgr-1 in morphogenesis and neurogenesis in the mouse,” Development, vol. 111, no. 2, pp. 531–542, 1991.
- J.-I. Miyazaki, S. Takaki, K. Araki et al., “Expression vector system based on the chicken β-actin promoter directs efficient production of interleukin-5,” Gene, vol. 79, no. 2, pp. 269–277, 1989.
- P. B. Ahrens, M. Solursh, and R. S. Reiter, “Stage-related capacity for limb chondrogenesis in cell culture,” Developmental Biology, vol. 60, no. 1, pp. 69–82, 1977.
- M. J. B. van den Hoff, F. F. M. Moorman, and W. H. Lamers, “Electroporation in ‘intracellular’ buffer increases cell survival,” Nucleic Acids Research, vol. 20, no. 11, article 2902, 1992.
- V. Turk, B. Turk, and D. Turk, “Lysosomal cysteine proteases: facts and opportunities,” The EMBO Journal, vol. 20, no. 17, pp. 4629–4633, 2001.
- A. Ishihara, K. M. Shields, A. S. Litsky et al., “Osteogenic gene regulation and relative acceleration of healing by adenoviral-mediated transfer of human BMP-2 or -6 in equine osteotomy and ostectomy models,” Journal of Orthopaedic Research, vol. 26, no. 6, pp. 764–771, 2008.
- D. B. Constam and E. J. Robertson, “Regulation of bone morphogenetic protein activity by pro domains and proprotein convertases,” Journal of Cell Biology, vol. 144, no. 1, pp. 139–149, 1999.
- Y. Cui, F. Jean, G. Thomas, and J. L. Christian, “BMP-4 is proteolytically activated by furin and/or PC6 during vertebrate embryonic development,” The EMBO Journal, vol. 17, no. 16, pp. 4735–4743, 1998.
- L. B. Zimmerman, J. M. de Jesús-Escobar, and R. M. Harland, “The Spemann organizer signal noggin binds and inactivates bone morphogenetic protein 4,” Cell, vol. 86, no. 4, pp. 599–606, 1996.
- E. Gazzerro, V. Gangji, and E. Canalis, “Bone morphogenetic proteins induce the expression of noggin, which limits their activity in cultured rat osteoblasts,” The Journal of Clinical Investigation, vol. 102, no. 12, pp. 2106–2114, 1998.
- J. Sun, F.-F. Zhuang, J. E. Mullersman et al., “BMP4 activation and secretion are negatively regulated by an intracellular Gremlin-BMP4 interaction,” Journal of Biological Chemistry, vol. 281, no. 39, pp. 29349–29356, 2006.
- G. Tardif, D. Hum, J.-P. Pelletier, C. Boileau, P. Ranger, and J. Martel-Pelletier, “Differential gene expression and regulation of the bone morphogenetic protein antagonists follistatin and gremlin in normal and osteoarthritic human chondrocytes and synovial fibroblasts,” Arthritis and Rheumatism, vol. 50, no. 8, pp. 2521–2530, 2004.
- L. Fischer, G. Boland, and R. S. Tuan, “Wnt signaling during BMP-2 stimulation of mesenchymal chondrogenesis,” Journal of Cellular Biochemistry, vol. 84, no. 4, pp. 816–831, 2002.