Comparison of ^99mTc-N-DBODC5 and ^99mTc-MIBI of Myocardial Perfusion Imaging for Diagnosis of Coronary Artery Disease

Table 4

Sensitivity, specificity, and diagnostic accuracy of scintigraphic perfusion studies and agreement with coronary angiography.

	Overall		LAD		LCX		RCA
	MIBI	DBODC	MIBI	DBODC	MIBI	DBODC	MIBI	DBODC
No. of disease	25	25	10	12	9	8	13	13
Sensitivity (%)	86	86	53	63	64	57	87	87
Specificity (%)	65	88	96	96	94	94	68	87
Accuracy (%)	78	87	78	83	85	83	74	87
^▲Kappa (𝜅)	0.53	0.73	0.52	0.63	0.62	0.55	0.48	0.71

Data are presented as number (%); MIBI = ^99mTc-MIBI, DBODC = ^99mTc-N-DBODC5; LAD: left anterior descending coronary artery; LCX: left circumflex coronary artery; RCA: right coronary artery. ^▲CA was used as the “gold standard” for the calculation of the 𝜅, which is determine between SPECT MPI and CA. If there is no agreement, 𝜅 = 0.20–0.39; moderate agreement, 𝜅 = 0.40–0.59; very good agreement, 𝜅 = 0.60–0.79; excellent agreement, 𝜅 = 0.80–1.00.