Table 8: Expected phenotype frequencies according to genotypes for the cytokines TNF- , IFN- , IL-6, IL-10, and TGF-β1.

PhenotypesGenotypesPatients ( )  
(%)
Controls ( )  
(%)

TNF
LowG/G 62 (78.48)73 (72.28)
HighG/A 17 (21.52) 28 (27.72)
A/A

IL6
HighG/G 72 (91.14) 87 (86.14)
G/C
LowC/C 7 (8.86)14 (13.86)

INFG
HighT/T 19 (24.36)19 (19.39)
Intermediate T/A 31 (39.74)50 (51.02)
Lowb A/A 28 (35.90)29 (29.59)

IL10
HighGCC/GCC 16 (20.51)12 (12.00)
IntermediateaGCC/ACC 25 (32.05) 48 (48.00)
GCC/ATA
LowACC/ACC 37 (47.44) 40 (40.00)
ACC/ATA
ATA/ATA

TGFB1
HighT/T  G/G 52 (65.82) 78 (78.00)
T/C  G/G
IntermediateT/C  G/C 22 (27.85) 17 (17.00)
C/C  G/G
T/T  G/C
LowC/C  G/C 5 (6.33) 5 (5.00)
C/C  C/C
T/T  C/C
T/C  C/C

: number of excepted phenotypes according to genotypes.
%: frequencies.
a ; OR = 0.1607; 95% CI = 0.276–0.947.
b ; OR = 1.81; 95% CI = 1.178–4.604.