Inhibition of Carrageenan-Induced Acute Inflammation in Mice by Oral Administration of Anthocyanin Mixture from Wild Mulberry and Cyanidin-3-Glucoside
Figure 2
Effect of C3G and AF on carrageenan-induced paw oedema. Footpad oedema was induced by injection of cg (0.5% w/v in saline, i.pl.) and was evaluated by plethysmometry. C3G or AF (4 mg/100 g body weight) or indomethacin (1 mg/kg, i.v.) or saline (control oedema) was orally administered in two different times: 30 min before (a) and 1 h after (b) i.pl. injection of cg. The increase paw size was measured 1, 2, 3, 4, and 5 h after cg injection. The time zero corresponds to cg injection. The results were expressed as mean ± EPM of 8 mice. Statistically significant difference regarding saline (control group) and C3G and AF and Indomethacin groups is expressed as .
