Biomarker Selection and Classification of “-Omics” Data Using a Two-Step Bayes Classification Framework

Table 1

Actual performance results on breast cancer (KRBDSR).

Criterion	Filter	Wrapper methods					Hybrid methods
	Fisher’s ratio	RFE-LNW-GD	RFE-SVM	RFE-LSSVM	RFE-RR	RFE-FLDA	RFE-LNW1	RFE-LNW2	RFE-FSVs-7DK	NB-HNB
Accuracy	0.88	0.78	0.76	0.75	0.74	0.75	0.82	0.88	0.85	0.91
Sensitivity, specificity	0.83, 0.90	0.77, 0.81	0.68, 0.80	0.68, 0.80	0.68, 0.77	0.69, 0.80	0.74, 0.88	0.82, 0.90	0.84, 0.86	0.91, 0.91
Number of genes selected	35	26	33	36	39	28	35	33	21	25