Biomarker Selection and Classification of “-Omics” Data Using a Two-Step Bayes Classification Framework

Table 3

Actual performance results on colon cancer (KRBDSR).

Criterion	Filter	Wrapper methods					Hybrid methods
	Fisher’s ratio	RFE-LNW-GD	RFE-SVM	RFE-LSSVM	RFE-RR	RFE-FLDA	RFE-LNW1	RFE-LNW2	RFE-FSVs-7DK	NB-HNB
Accuracy	0.90	0.87	0.87	0.91	0.83	0.89	0.91	0.89	0.91	0.93
Sensitivity, specificity	0.92, 0.88	0.89, 0.85	0.92, 0.79	0.97, 0.81	0.77, 0.91	0.93, 0.84	0.93, 0.88	0.93, 0.84	0.93, 0.89	0.93, 0.90
Number of genes selected	16	17	16	22	19	14	10	15	12	23