Human Mesenchymal Stem Cells Provide Protection against Radiation-Induced Liver Injury by Antioxidative Process, Vasculature Protection, Hepatocyte Differentiation, and Trophic Effects

Figure 2

Biochemical analysis of plasma samples at 7 days after TBI. Biochemical analyses of plasmatic urea, creatinine, and transaminases were performed on 200 μL of plasma taken on NOD/SCID mice subjected to TBI at 3.2 Gy. Abbreviations: ALT: serum alanine aminotransferase; AST: serum aspartate aminotransferase. (a) Decrease of plasmatic urea levels at 7 days after TBI. (b) Plasmatic creatinine levels at 7 days after TBI. ((c) and (d)) Increase of plasmatic AST and ALT, respectively, at 7 days after TBI. All values are expressed as the mean and the standard error of the mean (SEM). The significance for all analyses was set at 𝑃<0.01 (**) and 𝑃<0.001 (***), and nonsignificance was noted as ns. Each group was composed of 5 animals (𝑛=5).

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