Glutamine and Alanyl-Glutamine Increase RhoA Expression and Reduce Clostridium difficile Toxin-A-Induced Intestinal Epithelial Cell Damage
Figure 4
Electromicroscopy analysis of the effects of glutamine or alanyl-glutamine supplementation on IEC-6 cells following damage induced by Clostridium difficile’s TcdA. The IEC-6 cells were divided into 4 groups: control (a), treated with TcdA at 10 ng/mL for 24 h (b), treated with TcdA at 10 ng/mL for 24 h and supplemented with 10 mM Ala-Gln (c), treated with TcdA at 10 ng/mL for 24 h and 10 mM of Gln (d). The images were confectioned with SEM, magnification 9.45X and scale bar 5 μm.
