152909.fig.005a
(a) Mpg +/+ + KBrO3
152909.fig.005b
(b) Mpg +/+ + KBrO3
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(c) Mpg −/− + KBrO3
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(d) Mpg −/− + KBrO3
Figure 5: MTT and clonogenic survival curves for KBrO3 treatment of Mpg +/+ and Mpg −/− MEFs with and without reduced Msh2 expression. MTT (a) and clonogenic survival (b) curves for Mpg +/+ + pshRNAMsh2283, clone 9 (85% Msh2 gene silencing; black square), or Mpg +/+ + pshRNA empty (grey square) cells treated with KBrO3. MTT (c) and clonogenic survival (d) curves for Mpg −/− + pshRNAMsh2283, clone 1 (79% Msh2 gene silencing; solid square), or Mpg −/− + pshRNA empty (grey square) cells treated with KBrO3. Results are expressed as mean ± SEM; * , ** , and *** .