Table 1: Changes in resistancea to t-BOOH and KBrO3 in cell lines as a result of Msh2 knockdown in Nth1 +/+, Nth1 −/−, Mpg +/+, and Mpg −/− MEFs.

Cell line% Msh2 gene
silencing
t-BOOHKBrO3
MTTClonogenicMTTClonogenic

Nth1 +/+88%~↑
Nth1 −/−85%↑***↑***↑*
Mpg +/+85%↑***↑*
Mpg −/−79%↑*** **

Assessed by MTT and clonogenic assays.
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