Research Article

VEGF and bFGF Gene Polymorphisms in Patients with Non-Hodgkin's Lymphoma

Table 1

Patients characteristics.

CharacteristicsNHL patients ( )

Sex
 Female31
 Male47
Age
 <60 yrs51
 >60 yrs27
Ann Arbor stage
 I/II13
 III/IV65
B symptoms
 Absent13
 Present65
Serum LDH
 Normal49
 Elevated*29
Performance status (ECOG)
 <224
 ≥254
Number of extranodal sites
 <255
 ≥223
Serum β2-microglobulin
 Normal20
 Elevated35
 Unknown23
IPI risk groups
 Low/intermediate low (1, 2)40
 Intermediate high/high (3, 4)38
Histological aggressiveness
 Indolent40
  Follicular 17
  Small lymphocytic15
  Other B cells8
 Aggressive38
  Diffuse large B-cell lymphoma28
  Mantle5
  Lymphoblastic2
  Peripheral T cell3
Survival
 Dead47
 Alive31
Response to treatment
 Complete remission 35
 Partial remission30
 No response13

NHL: non-Hodgkin’s lymphoma; LDH: serum lactate dehydrogenase; ECOG: Eastern Cooperative Oncology Group; IPI: International Prognostic Index.
*>480 U/L; >1.80 mg/L.