Chronic Heat Stress Inhibits Immune Responses to H5N1 Vaccination through Regulating CD4+CD25+Foxp3+ Tregs
Figure 5
Adoptive transfer of CD4+CD25+ Tregs reduces the vaccine efficacy under TN conditions. 106 CD4+CD25+ Tregs from CHS+Ag group and TN+Ag group were adoptively transferred into TN+Ag mice on day 21 in conjunction with a 50 PFU H5N1 virus challenge. The mortalities of the two transferred groups () were observed for 14 days.