FISH probes abbreviations: SF(A): single fusion probe—LSI PML/RARA dual colour translocation probe (Abbott Molecular Inc.); DF(A): dual fusion probe—LSI PML/RARA dual colour dual fusion translocation probe (Abbott); BA(A): break apart probe—LSI RARA dual colour break apart rearrangement probe (Abbott); ES(C): extra signal probe—PML/RARA translocation probe (Cytocell); DF(C): dual fusion probe—PML/RARA translocation dual colour probe (Cytocell); NT: not tested; NA: not available; −: not visible; −/+: only visible via single band-pass filters; +: observed; #PML/RARA RT-PCR identification of the variant transcripts: 1 refers to the PML bcr1 within intron 6 and 2 to the PML bcr2 with variable breakpoints within exon 6 and 3 to PML bcr3 within intron 3 [13].