Multimolecular Salivary Mucin Complex Is Altered in Saliva of Cigarette Smokers: Detection of Disulfide Bridges by Raman Spectroscopy

Figure 2

Raman spectra of S-S stretch and amide I derived from disulfide bonds of saliva proteins (a) and the areal ratio of disulfide residues per amide I (b). The black line and grey line correspond to stimulated saliva and unstimulated (resting)　saliva, respectively. (c) Spectra similar to that of (a) of crystalline glutathione, GSH and GSSG forms, are presented with black and grey lines, respectively.

(a)

(b)

(c)