Peanut Sensitization Profiles in Italian Children and Adolescents with Specific IgE to Peanuts
Table 1
Clinical and laboratory features of the 48 children and adolescents with documented peanut sensitization (sIgE > 1 kUA/L). The patients have been categorized by the tolerance status against peanuts.
Study population ()
Tolerant patients ()
Avoiders ()
values Tolerant versus avoiders
Sex, male, (%)
30 (62)
12 (50)
18 (75)
NS
Age, median years (range)
8 (2–16)
9.5 (2–16)
8 (2–16)
NS
Parental history of atopy, (%)
21 (44)
8 (33)
13 (54)
NS
Allergic respiratory disease, (%)
26 (54)
13 (54)
13 (54)
NS
Age onset respiratory disease years, median (range)
6 (2–13)
6.5 (4–10)
4.5 (2–13)
NS
Atopic Dermatitis, (%)
27 (56)
11 (46)
16 (67)
NS
Age onset atopic dermatitis years, median (range)
0.5 (0.5–5)
0.8 (0.5–4)
0.5 (0.5–5)
NS
Food allergy, (%)
40 (83)
16 (67)
24 (100)
<0.005
Age onset food allergy years, median (range)
1 (0.5–11)
1 (0.5–6)
1.5 (0.5–11)
NS
Peanut avoiders, (%)
24 (50)
0
24 (100)
NA
Never eaten, (%)
20 (42)
0
20 (83)
NA
Clinical reactions, (%)
4 (8)
0
4 (17)
NA
Inhalant allergen sensitization, (%)
40 (83)
20 (83)
20 (83)
NS
Grass (Phleum p. and/or Cynodon d.), (%)
39 (81)
19 (79)
20 (83)
NS
Birch, (%)
36 (75)
17 (71)
19 (79)
NS
Bet v 1, (%)
18 (37)
7 (29)
9 (37)
NS
Hazel tree, (%)
36 (75)
18 (75)
18 (75)
NS
Olive tree, (%)
37 (77)
18 (75)
19 (79)
NS
Food allergen sensitization, (%)
48 (100)
24 (100)
24 (100)
NA
Peanut, (%)
48 (100)
24 (100)
24 (100)
NA
Ara h 1, (%)
6 (12.5)
0 (0)
6 (25)
<0.05
Ara h 2, (%)
13 (27)
3 (12)
10 (42)
<0.05
Ara h 3, (%)
11 (23)
4 (17)
7 (29)
NS
Ara h 8, (%)
17 (35)
8 (33)
9 (37)
NS
Ara h 9, (%)
28 (58)
17 (71)
11 (46)
NS
Hazelnut, (%)
43 (90)
21 (87)
22 (92)
NS
Walnut, (%)
34 (71)
15 (62)
19 (79)
NS
Rice, (%)
28 (58)
13 (54)
15 (62)
NS
Wheat, (%)
35 (73)
16 (67)
9 (37)
<0.05
Soy, (%)
33 (69)
13 (54)
20 (83)
<0.05
Apple, (%)
31 (65)
14 (58)
17 (71)
NS
Probability () values of less than 0.05 were considered significant. NA: not applicable; NS: not significant.
