New Morphological Features for Grading Pancreatic Ductal Adenocarcinomas

<table>Original lumen boundary <svg height="16.512501" id="M108" style="vertical-align:-0.0pt" version="1.1" viewbox="0 0 21.3375 16.512501" width="21.3375" xmlns="http://www.w3.org/2000/svg" xmlns:xlink="http://www.w3.org/1999/xlink">
<g transform="matrix(.017,-0,0,-.017,.062,16.45)"><path d="M426 365v-1q86 -11 139.5 -59t53.5 -117q0 -84 -72 -136q-71 -52 -202 -52h-329v25q54 6 71 21t17 57v467q0 44 -18.5 60.5t-69.5 20.5v25h317q121 0 186.5 -41.5t65.5 -118.5q0 -60 -38 -97t-121 -54zM264 592v-219q92 0 123 30q33 30 33 106q0 137 -99 137
q-30 0 -43.5 -12.5t-13.5 -41.5zM290 343h-26v-245q0 -36 15 -51t48 -15q58 0 89 40t31 116q0 155 -157 155z" id="x1D401"></path></g>
<g transform="matrix(.012,-0,0,-.012,11.4,8.287)"><path d="M743 335q0 -156 -100 -255q-99 -99 -255 -99q-155 0 -254 99t-99 254q0 159 101 258q100 99 258 99q151 0 250 -101q99 -100 99 -255zM566 328q0 160 -46.5 245t-134.5 85q-83 0 -128 -86t-45 -242q0 -158 46 -237t132 -79t131 80t45 234z" id="x1D40E"></path></g>
</svg> (green line) and ideal lumen boundary <svg height="16.325001" id="M109" style="vertical-align:-0.0pt" version="1.1" viewbox="0 0 16.7125 16.325001" width="16.7125" xmlns="http://www.w3.org/2000/svg" xmlns:xlink="http://www.w3.org/1999/xlink">
<g transform="matrix(.017,-0,0,-.017,.062,16.262)"><path d="M426 365v-1q86 -11 139.5 -59t53.5 -117q0 -84 -72 -136q-71 -52 -202 -52h-329v25q54 6 71 21t17 57v467q0 44 -18.5 60.5t-69.5 20.5v25h317q121 0 186.5 -41.5t65.5 -118.5q0 -60 -38 -97t-121 -54zM264 592v-219q92 0 123 30q33 30 33 106q0 137 -99 137
q-30 0 -43.5 -12.5t-13.5 -41.5zM290 343h-26v-245q0 -36 15 -51t48 -15q58 0 89 40t31 116q0 155 -157 155z" id="x1D401"></path></g>
<g transform="matrix(.012,-0,0,-.012,11.4,8.1)"><path d="M370 25v-25h-350v25q56 4 75 20q18 15 18 61v470q0 41 -19 56t-74 19v25h350v-25q-56 -2 -75.5 -17.5t-19.5 -57.5v-470q0 -48 18 -63q20 -14 77 -18z" id="x1D408"></path></g>
</svg> (red line).</table>

BioMed Research International

fig5

Figure 5

Figure 5: New Morphological Features for Grading Pancreatic Ductal Adenocarcinomas 