Downregulation of DLC-1 Gene by Promoter Methylation during Primary Colorectal Cancer Progression

Table 4

Correlation between DLC-1 mRNA expression and promoter methylation status in adenomas and CRCs.

mRNA expression	Unmethylation and Partial methylation (<10%)	Extensive methylation (≥10%)	𝑃 value
Reduced	62	31	0.022
Abundant	38	6