Research Article
Safety Assessment and Biological Effects of a New Cold Processed SilEmulsion for Dermatological Purpose
Table 6
Exposure data of formulation ingredients.
| Ingredient | Daily exposure (mg/kg bw/day) | % in the final product | Dermal absorption* | SED (mg/kg bw/day) |
| Bis-PEG/PPG-16/16 PEG/PPG-16/16 dimethicone (and) caprylic/capric triglyceride | 123.2 | 5.0 | 100 | 6.16 | PEG-20 glyceryl laurate | 123.2 | 4.0 | 100 | 4.93 | Isopropyl myristate | 123.2 | 5.0 | 100 | 6.16 | C12-15 alkyl benzoate | 123.2 | 5.0 | 100 | 6.16 | HPMC | 123.2 | 2.0 | 100 | 2.46 | PVM/MA | 123.2 | 0.3 | 100 | 0.37 | Cetrimide | 123.2 | 0.075 | 100 | 0.09 | 1,5-Pentanediol | 123.2 | 10.0 | 100 | 12.32 |
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When no permeation data is available, the value considered is 100%.
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