Elucidation of Novel Structural Scaffold in Rohu TLR2 and Its Binding Site Analysis with Peptidoglycan, Lipoteichoic Acid and Zymosan Ligands, and Downstream MyD88 Adaptor Protein
Figure 7
Interaction of TLR2-TIR and MyD88-TIR in Discovery Studio 2.5. (a) TLR2-TIR model is labeled as chain “A” and MyD88-TIR model is labeled as chain “B.” Interface residues are shown inside a rectangle box in ball and stick representation. (b) Clustering of interface residues between TLR2-TIR and MyD88-TIR domain in tree format. Residues of TLR2-TIR are marked as chain “A” and MyD88-TIR as chain “B.” Strongly interacting residues are highlighted with different colors.
