Table 1: (a) Optimised blank films prepared with different amounts of polymers and plasticiser and (b) films containing varying amounts of paracetamol and amoxicillin.
(a) Blank films

Mixture of polymers and plasticizerWeight ratios Total polymer weight (mg)

5 : 3 : 31100
SA : CMC : GLY5 : 3 : 6 1400
5 : 2 : 31000
CAR : CMC : SA : GLY2 : 2 : 2 : 3900
CAR : SA : GLY2 : 3 : 61100
CAR : CMC : GLY 1 : 2 : 3 600

(b) Drug loaded films

FormulationWeight without drug (mg)Weight of drug (mg)Total dry weight (mg)Drug loading (% of film dry weight)

Paracetamol

SA : CMC : GLY (5 : 3 : 3)110010012008.3
SA : CMC : GLY (5 : 3 : 3)1100150125012.0
SA : CMC : GLY (5 : 2 : 3)1000150115013.0
CAR : CMC : SA : GLY (2 : 2 : 2 : 3)900509505.3
CAR : CMC : SA : GLY (2 : 2 : 2 : 3)900759757.7
CAR : CMC : SA : GLY (2 : 2 : 2 : 3)900200110018.2
CAR : CMC : GLY (1 : 2 : 3)60025085029.4
CAR : CMC : GLY (1 : 2 : 3)60030090033.3
CAR : CMC : GLY (1 : 2  :  3)600400100040.0

Amoxicillin

SA : CMC : GLY (5 : 3 : 6)1400250165015.2
SA : CMC : GLY (5 : 3 : 6)1400300170017.6
SA : CMC : GLY (5 : 3 : 6)1400350175020.0
SA : CMC : GLY (5 : 3 : 6)1400400180022.2
SA : CMC : GLY (5 : 3 : 6)*1400500190026.3
CAR : SA : GLY (2 : 3 : 6)1100450155029.0
CAR : CMC : GLY (1 : 2 : 3)600500110045.5

Optimised paracetamol loaded films selected for further characterization.
*Optimised amoxicillin loaded films selected for further characterisation.