Table 1: Demographic and biological characteristics of the patients included in the population model.

Parameter Mean (range)

Gender (male : female)32 : 24
Age (years)57.4 (19–90)
Weight (kg)72.6 (50–110)
Height (cm)166.2 (148–182)
Serum creatinine (mg/dL)1.50 (0.60–6.26)
Creatinine clearance (mL/min)75.06 (7.81–177.10)
Total no. of peak concentrations collected85
Total no. of trough concentrations collected246