Urine Bikunin as a Marker of Renal Impairment in Fabry's Disease

Table 3

Urinary glycosaminoglycans/UTI levels and distribution in Fabry’s patients presenting with either only proteinuria or renal damage.

	RD Patients with proteinuria (𝑛 = 5)	RD Patients with renal damage (𝑛 = 6)	(𝑃)
Uronic acid (μgUA/mg Cr)	4.08 ± 1.40	4.91 ± 1.77	0.44
UTI (%)	52.7 ± 13.6	69.2 ± 18.8	0.16
HS (%)	23.8 ± 8.9	13.8 ± 9.2	0.11
CS (%)	23.5 ± 4.8	17.0 ± 10.3	0.27
UTI (μgUA/mg Cr)	2.27 ± 1.19	3.64 ± 1.96	0.24
HS (μgUA/mg Cr)	0.88 ± 0.07	0.55 ± 0.29	0.05
CS (μgUA/mg Cr)	0.92 ± 0.21	0.72 ± 0.22	0.18

GAGs/PGs levels are reported as μg of uronic acid (UA) per mg of creatinine.
UTI, HS and CS levels are calculated from total UA content and relative percentages of each GAG.