Table 10: T-ALL related genes in KEGG pathways [119].

Gene symbolGene title

SIX4SIX homeobox 4
LMO2LIM domain only 2 (rhombotin-like 1)
HPGD15-Hydroxyprostaglandin dehydrogenase (NAD)
GRIA3Glutamate receptor, ionotropic, and AMPA 3
EYA1Eyes absent homolog 1 (Drosophila)
FUT8Fucosyltransferase 8 (alpha (1,6) fucosyltransferase)
MLLMyeloid/lymphoid or mixed-lineage leukemia (trithorax homolog, Drosophila)
MEIS1Meis homeobox 1
HOXA9Homeobox A9
TLX1T-cell leukemia homeobox 1
CCR7Chemokine (C-C motif) receptor 7
LDB1LIM domain binding 1
CDKN2CCyclin-dependent kinase inhibitor 2C (p18, inhibits CDK4)
LYL1Lymphoblastic leukemia derived sequence 1
TCF3Transcription factor 3 (E2A immunoglobulin enhancer binding factors E12/E47)
HHEXHematopoietically expressed homeobox
SIX1SIX homeobox 1
HOXA11Homeobox A11
PTCRAPre-T-cell antigen receptor alpha
MLLT1Myeloid/lymphoid or mixed-lineage leukemia (trithorax homolog, Drosophila), translocated to 1
HOXA10Homeobox A10