Metabolomic Analysis of Differential Changes in Metabolites during ATP Oscillations in Chondrogenesis

Table 1

The fold changes in concentrations of metabolites increased significantly in peak of ATP oscillations.

Metabolite	Ratio; (peak/trough)	𝑃 value; (Welch’s t-test)
Fructose 1,6-bisphosphate	1.77	0.045
Malate	1.65	0.042
Fumaric acid	1.58	0.030
2-Oxoglutarate	1.57	0.047
1,3-Bisphosphoglycerate	1.52	0.041
cis-Aconitic acid	1.51	0.037
2-Phosphoglycerate	1.44	0.042
3-Phosphoglycerate	1.44	0.047
NADH	1.43	0.048
UDP-glucuronic acid	1.34	0.026
O-Acetylcarnitine	1.32	0.011
ATP	1.31	0.042
Phosphorylcholine	1.30	0.029
Glucuronic acid	1.16	0.023
Tyramine	1.11	0.049