Potential Utility of Sodium Selenate as an Adjunct to Metformin in Treating Type II Diabetes Mellitus in Rats: A Perspective on Protein Tyrosine Phosphatase
Figure 1
Glucose tolerance curve showing the effect of glucose (2 g/kg, p.o) in normal control, nontreated DIR, and treated rats with metformin, sodium selenate and their combination. Values represent the mean of 6 rats ± SEM (one-way ANOVA followed by LSD test). DIR: diabetic/insulin resistant, DIR + Met: diabetic/insulin resistant + metformin, DIR + Sel: diabetic/insulin resistant + sodium selenate, DIR + Met + Sel: diabetic/insulin resistant + metformin + sodium selenite.