Association of the KLF14 rs4731702 SNP and Serum Lipid Levels in the Guangxi Mulao and Han Populations
Table 4
Relationship between serum lipid parameters and relative factors in the Mulao and Han populations.
Lipid parameter
Risk factor
Unstandardized coefficient
Std. error
Standardized coefficient
Mulao and Han
TC
Waist circumference
0.020
0.004
0.135
5.142
0.000
Alcohol consumption
0.011
0.002
0.139
5.339
0.000
Age
0.236
0.044
0.138
5.363
0.000
Diastolic blood pressure
0.008
0.003
0.071
2.643
0.008
TG
Waist circumference
0.063
0.007
0.220
8.631
0.000
Alcohol consumption
0.331
0.093
0.100
3.568
0.000
Cigarette smoking
0.113
0.035
0.082
3.270
0.001
Blood glucose
0.396
0.123
0.090
3.227
0.001
HDL-C
Waist circumference
−0.009
0.002
−0.145
−4.028
0.000
Alcohol consumption
0.117
0.021
0.168
5.514
0.000
Gender
0.090
0.031
0.090
2.889
0.004
Body mass index
−0.014
0.005
−0.091
−2.607
0.009
LDL-C
Body mass index
0.052
0.007
0.193
7.642
0.000
Age
0.010
0.001
0.173
6.872
0.000
Genotype
0.089
0.031
0.072
2.867
0.004
Ethnic group
−0.123
0.044
−0.070
−2.765
0.006
ApoAI
Alcohol consumption
0.127
0.015
0.266
8.722
0.000
Waist circumference
−0.004
0.001
−0.086
−3.286
0.001
Gender
0.051
0.021
0.074
2.385
0.017
ApoB
Waist circumference
0.007
0.002
0.133
3.724
0.000
Ethnic group
−0.135
0.021
−0.161
−6.410
0.000
Blood glucose
0.023
0.006
0.092
3.624
0.000
Gender
−0.058
0.022
−0.069
−2.648
0.008
Systolic blood pressure
0.001
0.001
0.058
2.247
0.025
Body mass index
0.009
0.004
0.069
1.973
0.049
ApoAI/ApoB
Waist circumference
−0.011
0.003
−0.147
−4.130
0.000
Age
−0.003
0.001
−0.071
−2.741
0.006
Body mass index
−0.024
0.007
−0.122
−3.511
0.000
Ethnic group
0.092
0.032
0.072
2.856
0.004
Blood glucose
−0.025
0.010
−0.067
−2.577
0.010
Alcohol consumption
0.121
0.027
0.135
4.505
0.000
Gender
0.175
0.039
0.135
4.445
0.000
Mulao
TC
Body mass index
0.067
0.016
0.155
4.298
0.000
Alcohol consumption
0.251
0.065
0.140
3.871
0.000
Age
0.011
0.003
0.119
3.289
0.001
TG
Waist circumference
0.054
0.010
0.202
5.575
0.000
Alcohol consumption
0.497
0.113
0.160
4.418
0.000
HDL-C
Body mass index
−0.037
0.005
−0.248
−6.947
0.000
Alcohol consumption
0.118
0.027
0.194
4.443
0.000
Gender
0.105
0.040
0.115
2.631
0.009
LDL-C
Body mass index
0.054
0.011
0.185
5.121
0.000
Age
0.008
0.002
0.125
3.449
0.001
Genotype
0.101
0.046
0.080
2.203
0.028
ApoAI
Alcohol consumption
0.128
0.024
0.237
5.330
0.000
Gender
0.096
0.036
0.119
2.677
0.008
Genotype
0.049
0.020
0.088
2.404
0.016
ApoB
Waist circumference
0.011
0.002
0.177
4.801
0.000
Blood glucose
0.027
0.012
0.081
2.187
0.029
ApoAI/ApoB
Waist circumference
−0.018
0.003
−0.206
−5.680
0.000
Han
TC
Diastolic blood pressure
0.019
0.004
0.192
5.170
0.000
Alcohol consumption
0.249
0.057
0.154
4.407
0.000
Age
0.009
0.003
0.124
3.334
0.001
Waist circumference
0.017
0.005
0.121
3.338
0.001
Blood glucose
0.053
0.022
0.085
2.374
0.018
TG
Waist circumference
0.081
0.014
0.268
5.796
0.000
Cigarette smoking
0.903
0.151
0.203
5.964
0.000
Blood glucose
0.235
0.048
0.174
4.918
0.000
Diastolic blood pressure
0.035
0.008
0.164
4.461
0.000
Age
−0.019
0.006
−0.118
−3.209
0.001
Body mass index
−0.067
0.032
−0.095
−2.078
0.038
HDL-C
Waist circumference
−0.014
0.002
−0.206
−5.615
0.000
Alcohol consumption
0.075
0.029
0.095
2.597
0.010
LDL-C
Age
0.012
0.002
0.221
6.364
0.000
Body mass index
0.045
0.009
0.182
5.141
0.000
Cigarette smoking
−0.310
0.069
−0.196
−4.480
0.000
Gender
−0.292
0.076
−0.170
−3.840
0.000
Genotype
0.087
0.042
0.072
2.073
0.039
ApoAI
Alcohol consumption
0.116
0.017
0.295
7.001
0.000
Body mass index
−0.012
0.003
−0.152
−4.304
0.000
Cigarette smoking
0.075
0.022
0.151
3.350
0.001
Gender
0.067
0.025
0.124
2.651
0.008
ApoB
Waist circumference
0.005
0.001
0.193
4.302
0.000
Blood glucose
0.019
0.004
0.166
4.946
0.000
Alcohol consumption
0.030
0.012
0.097
2.548
0.011
Body mass index
0.009
0.003
0.151
3.471
0.001
Gender
−0.046
0.016
−0.111
−2.849
0.005
Diastolic blood pressure
0.002
0.001
0.110
3.137
0.002
Age
0.001
0.000
0.093
2.656
0.008
ApoAI/ApoB
Waist circumference
−0.009
0.003
−0.148
−3.190
0.001
Body mass index
−0.031
0.007
−0.211
−4.675
0.000
Age
−0.004
0.001
−0.108
−3.103
0.002
Blood glucose
−0.022
0.010
−0.078
−2.228
0.026
Alcohol consumption
0.091
0.030
0.122
3.009
0.003
Gender
0.230
0.047
0.225
4.868
0.000
Cigarette smoking
0.127
0.041
0.134
3.084
0.002
Genotype
−0.052
0.024
−0.072
−2.144
0.032
TC: total cholesterol; TG: triglyceride; HDL-C: high-density lipoprotein cholesterol; LDL-C: low-density lipoprotein cholesterol; ApoAI: apolipoprotein AI; ApoB: apolipoprotein B; ApoAI/ApoB: the ratio of apolipoprotein AI to apolipoprotein B.