Association of the KLF14 rs4731702 SNP and Serum Lipid Levels in the Guangxi Mulao and Han Populations
Table 5
Relationship between serum lipid parameters and relative factors in males and females of the Mulao and Han populations.
Lipid parameter
Risk factor
Unstandardized coefficient
Std. error
Standardized coefficient
Mulao/male
TC
Body mass index
0.084
0.026
0.174
3.183
0.002
Alcohol consumption
0.251
0.090
0.152
2.790
0.006
TG
Waist circumference
0.082
0.020
0.227
4.181
0.000
Alcohol consumption
0.412
0.194
0.115
2.119
0.035
HDL-C
Alcohol consumption
0.124
0.029
0.227
4.231
0.000
Body mass index
−0.036
0.009
−0.226
−4.218
0.000
LDL-C
Body mass index
0.045
0.016
0.157
2.828
0.005
Genotype
0.154
0.068
0.126
2.257
0.025
ApoAI
Alcohol consumption
0.127
0.025
0.264
4.978
0.000
Genotype
0.102
0.032
0.168
3.167
0.002
ApoB
Waist circumference
0.008
0.004
0.127
2.301
0.022
ApoAI/ApoB
Waist circumference
−0.016
0.004
−0.217
−4.003
0.000
Alcohol consumption
0.136
0.040
0.185
3.418
0.001
Mulao/female
TC
Age
0.015
0.004
0.181
3.714
0.000
Body mass index
0.054
0.019
0.138
2.835
0.005
TG
Waist circumference
0.026
0.007
0.194
3.968
0.000
HDL-C
Body mass index
−0.038
0.007
−0.273
−5.687
0.000
LDL-C
Body mass index
0.064
0.014
0.213
4.477
0.000
Age
0.013
0.003
0.211
4.425
0.000
ApoB
Waist circumference
0.013
0.003
0.209
4.356
0.000
Cigarette smoking
1.198
0.342
0.167
3.504
0.001
Blood glucose
0.037
0.018
0.102
2.079
0.038
Age
0.003
0.002
0.097
1.987
0.048
ApoAI/ApoB
Waist circumference
−0.019
0.005
−0.182
−3.736
0.000
Age
−0.008
0.003
−0.140
−2.878
0.004
Han/male
TC
Diastolic blood pressure
0.032
0.005
0.312
5.908
0.000
Alcohol consumption
0.213
0.071
0.158
2.988
0.003
TG
Waist circumference
0.079
0.022
0.194
3.569
0.000
Cigarette smoking
1.254
0.280
0.235
4.482
0.000
Blood glucose
0.440
0.106
0.228
4.141
0.000
Diastolic blood pressure
0.055
0.016
0.189
3.466
0.001
Age
−0.024
0.011
−0.116
−2.077
0.039
HDL-C
Waist circumference
−0.015
0.003
−0.287
−5.446
0.000
Alcohol consumption
0.100
0.026
0.202
3.842
0.000
Genotype
−0.073
0.034
−0.113
−2.163
0.031
Blood glucose
−0.027
0.013
−0.108
−2.052
0.041
LDL-C
Cigarette smoking
−0.330
0.074
−0.241
−4.479
0.000
Body mass index
0.040
0.012
0.180
3.351
0.001
ApoAI
Alcohol consumption
0.120
0.017
0.358
6.938
0.000
Body mass index
−0.012
0.004
−0.160
−3.146
0.002
Cigarette smoking
0.072
0.024
0.157
3.021
0.003
Genotype
−0.059
0.022
−0.137
−2.725
0.007
ApoB
Waist circumference
0.005
0.002
0.202
3.283
0.001
Diastolic blood pressure
0.004
0.001
0.210
4.062
0.000
Blood glucose
0.019
0.006
0.158
3.136
0.002
Alcohol consumption
0.032
0.012
0.135
2.683
0.008
Body mass index
0.007
0.003
0.136
2.219
0.027
ApoAI/ApoB
Body mass index
−0.027
0.007
−0.220
−3.621
0.000
Alcohol consumption
0.102
0.028
0.184
3.610
0.000
Waist circumference
−0.012
0.004
−0.204
−3.372
0.001
Genotype
−0.124
0.036
−0.173
−3.485
0.001
Cigarette smoking
0.113
0.039
0.148
2.889
0.004
Han/female
TC
Age
0.023
0.003
0.325
6.993
0.000
Body mass index
0.061
0.016
0.176
3.925
0.000
Blood glucose
0.054
0.026
0.096
2.069
0.039
TG
Waist circumference
0.046
0.008
0.265
5.645
0.000
Blood glucose
0.107
0.032
0.153
3.370
0.001
Diastolic blood pressure
0.016
0.005
0.138
2.942
0.003
HDL-C
Waist circumference
−0.011
0.004
−0.129
−2.669
0.008
LDL-C
Age
0.020
0.003
0.342
7.574
0.000
Waist circumference
0.021
0.005
0.183
4.071
0.000
Alcohol consumption
−0.008
0.004
−0.097
−2.155
0.032
Genotype
0.109
0.052
0.095
2.120
0.035
ApoAI
Alcohol consumption
−0.012
0.004
−0.138
−2.852
0.005
Body mass index
0.003
0.001
0.114
2.353
0.019
ApoB
Waist circumference
0.005
0.002
0.187
2.647
0.008
Blood glucose
0.021
0.005
0.194
4.254
0.000
Age
0.002
0.001
0.146
2.969
0.003
Body mass index
0.010
0.005
0.155
2.202
0.028
ApoAI/ApoB
Age
−0.007
0.002
−0.207
−4.291
0.000
Body mass index
−0.050
0.008
−0.285
−6.316
0.000
Cigarette smoking
0.043
0.012
0.165
3.531
0.000
Blood glucose
−0.031
0.013
−0.110
−2.343
0.020
TC: total cholesterol; TG: triglyceride; HDL-C: high-density lipoprotein cholesterol; LDL-C: low-density lipoprotein cholesterol; ApoAI: Apolipoprotein AI; ApoB: Apolipoprotein B; ApoAI/ApoB: the ratio of Apolipoprotein AI to Apolipoprotein B.