Table 2: Associations of BMP4 SNPs with type 2 diabetes.

SNP Chr. position (Build 37.3) Major/minor allele Risk alleleCases ( )Controls ( ) OR for risk allele (95% CI)P value for risk allele OR for genotype (95% CI)P value for genotype (empirical P value)
Risk allele frequenciesGenotype count
11/12/22#
Risk allele frequenciesGenotype count
11/12/22#

rs195186754407192G/CG0.9032748/586/350.8962673/617/361.073 (0.959, 1.201)0.2201.071 (0.957, 1.198)0.233
rs714604054407920A/GG0.0972755/586/360.0962768/572/381.017 (0.908, 1.140)0.7670.983 (0.878, 1.101)0.769
rs444423554410919T/CC0.459996/167/7170.4521034/1593/7161.026 (0.959, 1.098)0.4610.975 (0.912, 1.043)0.465
rs1756354417522T/CT0.7201800/1319/2730.7171733/1375/2691.042 (0.967, 1.124)0.2801.042 (0.967, 1.123)0.283
rs207104754418411C/TT0.3681380/1522/4850.3551428/1527/4441.056 (0.985, 1.133)0.1260.948 (0.885, 1.016)0.131
rs276188754425052C/AA0.519793/1675/9200.511795/1674/8661.033 (0.965, 1.105)0.3480.968 (0.905, 1.036)0.348
rs801407154431500A/GG0.3501426/1572/4040.3411462/1539/3861.039 (0.968, 1.115)0.2900.962 (0.896, 1.033)0.287
rs801436354431575T/CT0.8842617/690/450.8732574/774/451.108 (0.999, 1.229)0.0511.110 (1.000, 1.231)0.050 (0.3689)
rs714178554433114C/TC0.9042740/572/360.9022727/594/321.028 (0.916, 1.154)0.6391.022 (0.912, 1.146)0.705
rs657292754433390T/AT0.6331345/1534/4560.6321327/1533/4551.008 (0.940, 1.082)0.8161.008 (0.939, 1.081)0.834

P values <0.1 were shown in bold.
The additive model was used in the association analyses between genotype and type 2 diabetes.
11: major allele homozygotes; 12: heterozygotes; 22: minor allele homozygotes. Empirical P values are for the alleles based on 10,000 permutations.