Table 3: Associations of three haplotypes in BMP4 region with type 2 diabetes.

Haplotype Haplotype frequenciesP value (empirical P value)
CasesControls

Block1 (rs1951867-rs7146040)
 GA0.8050.8010.522
 CA0.0970.1030.248
 GG0.0970.0960.755
Block2 (rs17563-rs2071047)
 TT0.3680.3550.116
 TC0.3580.3610.688
 CC0.2740.2840.210
Block3 (rs8014071-rs8014363-rs7141785-rs6572927)
 ATCA0.3650.3660.960
 GTCT0.3480.3380.223
 ACCT0.1170.1270.056 (0.4263)
 ATTT0.0960.0980.705
 ATCT0.0730.0680.247

P values <0.1 were shown in bold.
Empirical P values are for the haplotypes based on 10,000 permutations.