Table 4: Association analyses of the rs8014363 genotype with clinical characteristics in the normal glucose tolerant group.

CC ( )CT ( )TT ( )βSEP P *

Age (years) 0.78920.53170.138/
BMI (kg/m2)22.98 (21.48, 24.65)23.26 (21.12, 25.53)23.23 (21.30, 25.51)0.00030.00220.884/
Fasting plasma glucose (mmol/L)5.06 (4.60, 5.40)5.00 (4.63, 5.39)5.03 (4.70, 5.40)0.00150.00170.3710.462
2 h plasma glucose (mmol/L)5.09 (4.50, 6.14)5.44 (4.70, 6.30)5.43 (4.60, 6.34)0.00170.00350.6370.888
Fasting insulin (mU/L)5.41 (3.39, 6.52)6.00 (4.23, 8.34)6.23 (4.39, 8.72)0.01810.01150.1140.127
2 h insulin (mU/L)29.36 (12.43, 51.29)28.34 (14.07, 45.17)27.81 (16.10, 47.10)0.01820.01580.2490.365
Total cholesterol (mmol/L)4.75 (4.04, 5.25)4.64 (4.01, 5.32)4.70 (4.05, 5.35)0.00340.00360.3410.643
Triglyceride (mmol/L)1.11 (0.74, 1.71)1.24 (0.84, 1.82)1.26 (0.88, 1.83)0.01880.00870.0310.035
HDL-C (mmol/L)1.38 (1.19, 1.58)1.34 (1.14, 1.52)1.33 (1.12, 1.51)−0.00540.00360.1340.068
LDL-C (mmol/L)3.00 (2.45, 3.62)3.03 (2.45, 3.60)3.04 (2.50, 3.62)0.00310.00490.5270.846
HOMA-IR1.13 (0.79, 1.56)1.27 (0.91, 1.89)1.34 (0.93, 1.91)0.02010.01190.0920.104
HOMA-B79.81 (47.82, 128.65)89.25 (61.45, 137.90)90.30 (62.92, 135.68)0.01150.01280.3690.382
Gutt-ISI104.36 (83.45, 138.38)100.24 (81.62, 131.43)99.56 (80.97, 127.80)−0.00950.00680.1600.220

Data are shown as mean ± SD or median (interquartile range).
BMI: body mass index; HDL-C: high-density lipoprotein cholesterol; LDL-C: low-density lipoprotein cholesterol; HOMA-IR: homeostasis assessment model of insulin resistance; HOMA-B: homeostasis assessment model of β-cell function; Gutt-ISI: insulin sensitivity index proposed by Gutt.
P values <0.1 were shown in bold.
Adjusted for age, gender, and BMI.