Research Article

Synthesis, Characterisation, and In Vitro Anticancer Activity of Curcumin Analogues Bearing Pyrazole/Pyrimidine Ring Targeting EGFR Tyrosine Kinase

Figure 5

(a) Compound 3 is represented with macromodel stick model. The hydrophobic cavity residues are represented with magenta stick model. The hydrogen bonds are shown with yellow colour dotted lines and hydrophobic interactions with orange dotted lines. (b) Compound 3 at binding site on surface.
239354.fig.005a
(a)
239354.fig.005b
(b)