Synthesis, Characterization, and Acute Oral Toxicity Evaluation of pH-Sensitive Hydrogel Based on MPEG, Poly(ε-caprolactone), and Itaconic Acid

Table 4

Hematology routine test of acute oral toxicity test.

	Female control group	Female treatment group	Male control group	Male treatment group
WBC (10^9/L)	6.01±1.10	4.45±0.59^∗	3.86±0.69	4.06±0.50
RBC (10^12/L)	11.13±0.51	11.36±0.39	11.11±0.37	11.33±0.38
HGB (g/L)	149.57±5.47	152.63±3.29	145.57±3.95	151.50±6.00
HCT (%)	58.17±0.89	59.85±1.53	57.30±0.88	61.25±1.77^∗
PLT (10^9/L)	537.43±108.23	666.38±121.95	635.86±56.57	666.38±48.92
MCV (fL)	51.77±1.18	52.33±0.93	52.79±0.90	53.84±0.80
MCH (pg)	13.37±0.31	13.36±0.39	13.09±0.38	13.31±0.25
MCHC (g/L)	258.14±3.72	255.38±6.12	247.71±4.92	247.38±4.37
RDW (%CV)	16.89±2.98	17.34±0.92	17.31±0.80	17.53±0.70
MPV (fL)	5.53±0.68	5.80±0.55	5.39±0.47	5.70±0.25
PDW (%)	13.54±0.81	14.77±0.81	14.05±0.79	15.06±0.87

∗P ≤ 0.05 compared to control group.