Synthesis, Characterization, and Acute Oral Toxicity Evaluation of pH-Sensitive Hydrogel Based on MPEG, Poly(ε-caprolactone), and Itaconic Acid

Table 5

Serum chemistry analysis of acute oral toxicity test.

	Female control group	Female treatment group	Malecontrol group	Male treatment group
ALB	35.61±1.57	35.00±0.76	34.07±1.35	34.34±1.13
ALP	220.57±16.24	236.38±29.60	225.00±29.30	206.00±15.89
ALT	51.86±18.77	43.75±6.23	42.43±3.21	42.13±4.58
AST	113±14.60	109.38±12.64	102.00±26.88	100.88±19.11
BUN	9.01±0.55	10.02±1.10^∗	9.89±1.47	9.45±0.99
CREA	1.86±1.46	2.33±1.06^∗	2.43±1.51	2.90±0.76
GLU	3.61±0.56	3.98±0.54	5.37±1.34	5.32±0.88
TBIL	0.07±0.19	0.27±0.24	0.37±0.33	0.21±0.22
TP	62.54±3.37	60.78±1.89	60.31±2.46	61.44±2.00

∗P ≤ 0.05 compared to control group.