MDR Gene Expression Analysis of Six Drug-Resistant Ovarian Cancer Cell Lines
Figure 1
MTT cell survival assay. W1, W1MR, W1CR, W1DR, W1VR, W1TR, and W1PR cells were seeded at density of 5000 cells/well in 96-well plates and treated with or without increasing concentration of methotrexate (a), cisplatin (b), doxorubicin (c), vincristine (d), topotecan (e), and paclitaxel (f), at 37°C for 72 h, and viability of cells was determined. The experiments were repeated three times, and each concentration was tested in triplicate in each experiment. Viability was expressed as a percent on an untreated control (mean ± SEM).
