MDR Gene Expression Analysis of Six Drug-Resistant Ovarian Cancer Cell Lines

Table 3

Correlation between transcript level and IC50 for cytostatic drugs (Pearson correlation—𝑅²).

Gene	Cytostatic drug
	Methotrexate	Cisplatin	Doxorubicin	Vincristine	Topotecan	Paclitaxel
MDR1	0.06	0.03	0.96***	0.97***	0.3	0.96***
MRP2	0.99***	0.06	0.05	0.05	0.09	0.05
BCRP	0.02	0.01	0.03	0.04	0.44	0.03

Values were considered significant at ***𝑃<0.001.