Research Article
MDR Gene Expression Analysis of Six Drug-Resistant Ovarian Cancer Cell Lines
Table 4
Correlation between protein levels and IC50 for cytostatic drugs (Pearson correlation—
).
| Gene | Cytostatic drug | Methotrexate | Cisplatin | Doxorubicin | Vincristine | Topotecan | Paclitaxel |
| MDR1 | 0.0549 | 0.0278 |
0.9483*** |
0.9658*** | 0.3067 |
0.9486*** | MRP2 | 0.088 | 0.1529 | 0.225 | 0.2388 | 0.4828 | 0.254 | BCRP | 0.0276 | 0.0019 | 0.0432 | 0.0499 | 0.4059 | 0.0442 |
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