Research Article

Viability Reduction and Rac1 Gene Downregulation of Heterogeneous Ex-Vivo Glioma Acute Slice Infected by the Oncolytic Newcastle Disease Virus Strain V4UPM

Figure 2

EGAS viability progression analysis and subsequent assessment in an organotypic culture following the excision from the patient and maintenance as EGAS in aCSF for 7 hours (represented as 0 hour in organotypic culture), the NDV-V4UPM treated EGAS showed a significant** reduction in the number of viable cells until 48 hours but regrowth at 72 hours, whilst mock-infected EGAS showed persistent growth with an increased number of viable cells. Error bars represent the ±SE.
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