Research Article

Metabolite Profile Resulting from the Activation/Inactivation of 1-Methyl-4-phenyl-1,2,3,6-tetrahydropyridine and 2-Methyltetrahydro-β-carboline by Oxidative Enzymes

Figure 2

Proposed activation and inactivation routes and metabolites from MPTP and 2-methyl-1,2,3,4-tetrahydro-β-carboline (2-Me-THβC) protoxins resulting from human monoamine oxidase (MAO), heme peroxidases (lactoperoxidase and myeloperoxidase), and human cytochrome P450 2D6.
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