Research Article

Metabolite Profile Resulting from the Activation/Inactivation of 1-Methyl-4-phenyl-1,2,3,6-tetrahydropyridine and 2-Methyltetrahydro-β-carboline by Oxidative Enzymes

Figure 3

HPLC chromatograms of MPTP oxidized by human MAO-B (a) and MPTP oxidized by human cytochrome P450 2D6 (b). Enzyme assays and chromatographic conditions were as indicated in experimental section.
248608.fig.003a
(a)
248608.fig.003b
(b)