Multiclass Prediction with Partial Least Square Regression for Gene Expression Data: Applications in Breast Cancer Intrinsic Taxonomy

Table 4

Single sample prediction by PAM50 centroids and predicted subtypes by PLS-regression for independent validation dataset.

PAM50 SSP; (sample number)	Predicted subtype
	Basal-like	HER2-enriched	Luminal-A	Luminal-B	Normal; breast-like	Unclassified
Basal-like (97)	83	1	0	1	0	12
HER2-enriched (94)	0	63	0	3	0	28
Luminal-A (165)	0	3	130	8	0	24
Luminal-B (121)	0	5	10	73	0	33
Normal breast-like (56)	1	3	17	1	8	26
Unclassified (2)	0	0	0	0	0	2