Table 1: Flow cytometric assessment of activation markers by AM.

MarkerPercentage of F4/80+ AM staining positiveMean fluorescence intensity (relative units)
NaïveAcute exacerbationNaïveAcute exacerbation

CD11b 3.43 ± 0.169.72 ± 1.62**48.73 ± 5.2795.53 ± 13.49**
CD11c88.37 ± 1.0692.05 ± 0.61*81.97 ± 1.62140.0 ± 4.93***
CD1498.90 ± 0.1298.17 ± 0.1545.67 ± 0.68190.8 ± 2.68***
CD1698.18 ± 0.1554.48 ± 1.70***32.37 ± 0.8219.97 ± 0.58***
CD234.31 ± 0.335.85 ± 0.14**28.94 ± 0.3128.38 ± 0.28
CD6474.08 ± 1.7462.77 ± 1.52**15.93 ± 0.2816.37 ± 0.37
CD8081.83 ± 1.0676.42 ± 0.5817.12 ± 0.2417.75 ± 0.17
CD8661.35 ± 1.4070.60 ± 1.92**19.58 ± 0.2129.83 ± 0.47***
MHCII31.33 ± 1.6255.93 ± 1.88***171.8 ± 2.12460.8 ± 22.34***

Data are mean ± SEM ( animals per group). Significant differences relative to naïve animals are shown as *( ), **( ), and ***( ).