- About this Journal
- Abstracting and Indexing
- Aims and Scope
- Annual Issues
- Article Processing Charges
- Articles in Press
- Author Guidelines
- Bibliographic Information
- Citations to this Journal
- Contact Information
- Editorial Board
- Editorial Workflow
- Free eTOC Alerts
- Publication Ethics
- Reviewers Acknowledgment
- Submit a Manuscript
- Subscription Information
- Table of Contents
BioMed Research International
Volume 2013 (2013), Article ID 251098, 7 pages
Long Noncoding RNA HOTAIR Is Associated with Motility, Invasion, and Metastatic Potential of Metastatic Melanoma
1The Affiliated Shenzhen Hospital, Anhui Medical University, Hefei, Anhui 230001, China
2Biomedical Research Institute, Shenzhen PKU-HKUST Medical Center, Shenzhen, Guangdong 518036, China
3Shenzhen Key Lab for Translational Medicine of Dermatology, Shenzhen PKU-HKUST Medical Center, Shenzhen, Guangdong 518036, China
4Shenzhen Key Discipline of Dermatology, Shenzhen Hospital, Peking University, Shenzhen, Guangdong 518036, China
5Department of Dermatology, Shenzhen Hospital, Peking University, Shenzhen, Guangdong 518036, China
Received 22 February 2013; Accepted 21 May 2013
Academic Editor: Marcelo Palma Sircili
Copyright © 2013 Lihua Tang et al. This is an open access article distributed under the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.
- E. G. Little and M. J. Eide, “Update on the current state of melanoma incidence,” Dermatologic Clinics, vol. 30, pp. 355–361, 2012.
- C. D. Malone and G. J. Hannon, “Small RNAs as guardians of the genome,” Cell, vol. 136, no. 4, pp. 656–668, 2009.
- D. Moazed, “Small RNAs in transcriptional gene silencing and genome defence,” Nature, vol. 457, no. 7228, pp. 413–420, 2009.
- C. A. Brosnan and O. Voinnet, “The long and the short of noncoding RNAs,” Current Opinion in Cell Biology, vol. 21, no. 3, pp. 416–425, 2009.
- J. S. Mattick, “Non-coding RNAs: the architects of eukaryotic complexity,” EMBO Reports, vol. 2, no. 11, pp. 986–991, 2001.
- N. Schöler, C. Langer, H. Döhner, C. Buske, and F. Kuchenbauer, “Serum microRNAs as a novel class of biomarkers: a comprehensive review of the literature,” Experimental Hematology, vol. 38, no. 12, pp. 1126–1130, 2010.
- Y. Xie, N. W. Todd, Z. Liu et al., “Altered miRNA expression in sputum for diagnosis of non-small cell lung cancer,” Lung Cancer, vol. 67, no. 2, pp. 170–176, 2010.
- L. Xing, N. W. Todd, L. Yu, H. Fang, and F. Jiang, “Early detection of squamous cell lung cancer in sputum by a panel of microRNA markers,” Modern Pathology, vol. 23, no. 8, pp. 1157–1164, 2010.
- P. Bertone, V. Stolc, T. E. Royce et al., “Global identification of human transcribed sequences with genome tiling arrays,” Science, vol. 306, no. 5705, pp. 2242–2246, 2004.
- P. Kapranov, J. Drenkow, J. Cheng et al., “Examples of the complex architecture of the human transcriptome revealed by RACE and high-density tiling arrays,” Genome Research, vol. 15, no. 7, pp. 987–997, 2005.
- V. Srikantan, Z. Zou, G. Petrovics et al., “PCGEM1, a prostate-specific gene, is overexpressed in prostate cancer,” Proceedings of the National Academy of Sciences of the United States of America, vol. 97, no. 22, pp. 12216–12221, 2000.
- M. J. G. Bussemakers, A. Van Bokhoven, G. W. Verhaegh et al., “DD3: a new prostate-specific gene, highly overexpressed in prostate cancer,” Cancer Research, vol. 59, no. 23, pp. 5975–5979, 1999.
- G. Petrovics, W. Zhang, M. Makarem et al., “Elevated expression of PCGEM1, a prostate-specific gene with cell growth-promoting function, is associated with high-risk prostate cancer patients,” Oncogene, vol. 23, no. 2, pp. 605–611, 2004.
- A. Iacoangeli, Y. Lin, E. J. Morley et al., “BC200 RNA in invasive and preinvasive breast cancer,” Carcinogenesis, vol. 25, no. 11, pp. 2125–2133, 2004.
- P. Ji, S. Diederichs, W. Wang et al., “MALAT-1, a novel noncoding RNA, and thymosin β4 predict metastasis and survival in early-stage non-small cell lung cancer,” Oncogene, vol. 22, no. 39, pp. 8031–8041, 2003.
- R. A. Gupta, N. Shah, K. C. Wang et al., “Long non-coding RNA HOTAIR reprograms chromatin state to promote cancer metastasis,” Nature, vol. 464, no. 7291, pp. 1071–1076, 2010.
- T. Gutschner and S. Diederichs, “The Hallmarks of Cancer: a long non-coding RNA point of view,” RNA Biology, vol. 9, no. 6, pp. 703–719, 2012.
- S. Boissier, M. Ferreras, O. Peyruchaud et al., “Bisphosphonates inhibit breast and prostate carcinoma cell invasion, an early event in the formation of bone metastases,” Cancer Research, vol. 60, no. 11, pp. 2949–2954, 2000.
- K. V. Prasanth and D. L. Spector, “Eukaryotic regulatory RNAs: an answer to the “genome complexity” conundrum,” Genes and Development, vol. 21, no. 1, pp. 11–42, 2007.
- D. S. Perez, T. R. Hoage, J. R. Pritchett et al., “Long, abundantly expressed non-coding transcripts are altered in cancer,” Human Molecular Genetics, vol. 17, no. 5, pp. 642–655, 2008.
- M. Guttman, J. Donaghey, B. W. Carey et al., “LincRNAs act in the circuitry controlling pluripotency and differentiation,” Nature, vol. 477, no. 7364, pp. 295–300, 2011.
- R. W. Carthew and E. J. Sontheimer, “Origins and mechanisms of miRNAs and siRNAs,” Cell, vol. 136, no. 4, pp. 642–655, 2009.
- L. Lipovich, R. Johnson, and C.-Y. Lin, “MacroRNA underdogs in a microRNA world: evolutionary, regulatory, and biomedical significance of mammalian long non-protein-coding RNA,” Biochimica et Biophysica Acta, vol. 1799, no. 9, pp. 597–615, 2010.
- M. Huarte and J. L. Rinn, “Large non-coding RNAs: missing links in cancer?” Human Molecular Genetics, vol. 19, no. 2, pp. R152–R161, 2010.
- Y.-S. Kim, J. Do Hwan, S. Bae, D.-H. Bae, and W. Ahn Shick, “Identification of differentially expressed genes using an annealing control primer system in stage III serous ovarian carcinoma,” BMC Cancer, vol. 10, article 576, 2010.
- I. J. Matouk, I. Abbasi, A. Hochberg, E. Galun, H. Dweik, and M. Akkawi, “Highly upregulated in liver cancer noncoding RNA is overexpressed in hepatic colorectal metastasis,” European Journal of Gastroenterology and Hepatology, vol. 21, no. 6, pp. 688–692, 2009.
- X. Zhang, R. Gejman, A. Mahta et al., “Maternally expressed gene 3, an imprinted noncoding RNA gene, is associated with meningioma pathogenesis and progression,” Cancer Research, vol. 70, no. 6, pp. 2350–2358, 2010.
- X.-S. Wang, Z. Zhang, H.-C. Wang et al., “Rapid identification of UCA1 as a very sensitive and specific unique marker for human bladder carcinoma,” Clinical Cancer Research, vol. 12, no. 16, pp. 4851–4858, 2006.
- K. Kim, I. Jutooru, G. Chadalapaka et al., “HOTAIR is a negative prognostic factor and exhibits pro-oncogenic activity in pancreatic cancer,” Oncogene, vol. 32, pp. 1616–1625, 2013.
- Z. Yang, L. Zhou, L.-M. Wu et al., “Overexpression of long non-coding RNA HOTAIR predicts tumor recurrence in hepatocellular carcinoma patients following liver transplantation,” Annals of Surgical Oncology, vol. 18, no. 5, pp. 1243–1250, 2011.
- Y. J. Geng, S. L. Xie, Q. Li, J. Ma, and G. Y. Wang, “Large intervening non-coding RNA HOTAIR is associated with hepatocellular carcinoma progression,” Journal of International Medical Research, vol. 39, no. 6, pp. 2119–2128, 2011.
- R. J. Flockhart, D. E. Webster, K. Qu et al., “BRAFV600E remodels the melanocyte transcriptome and induces BANCR to regulate melanoma cell migration,” Genome Research, vol. 22, pp. 1006–1014, 2012.
- K. Yamada, J. Kano, H. Tsunoda et al., “Phenotypic characterization of endometrial stromal sarcoma of the uterus,” Cancer Science, vol. 97, no. 2, pp. 106–112, 2006.
- R. Lin, S. Maeda, C. Liu, M. Karin, and T. S. Edgington, “A large noncoding RNA is a marker for murine hepatocellular carcinomas and a spectrum of human carcinomas,” Oncogene, vol. 26, no. 6, pp. 851–858, 2007.