Research Article
Molecular Modeling of Lectin-Like Protein from Acacia farnesiana Reveals a Possible Anti-Inflammatory Mechanism in Carrageenan-Induced Inflammation
Table 2
The overall interactions between AFAL and carrageenan.
| | CARRAGEENAN | Ser129 | Ala131 | Leu156 | Ser172 | Asp173 | Arg174 | Ile130 | Glu180 | Ala108 | | O | OG | O | N | O | O | OD2 | O | O | N | OE2 | O |
| | G4S31 | | | | | | | | | | | | | | O1 | 2.8 | — | — | — | — | — | — | — | — | 3.2 | — | — | | O2 | 3.2 | — | — | — | — | — | — | — | — | — | — | — | | G4S5 | | | | | | | | | | | | | | O2 | — | — | — | — | — | — | — | — | 3.1 | — | — | — | | O6 | — | — | — | — | — | — | — | — | — | — | 3.3 | — | | O7 | — | — | — | — | — | — | — | — | — | — | — | 3.2 | | DGS22 | | | | | | | | | | | | | | O7 | — | — | 2.5 | 2.3 | — | — | — | — | — | — | — | — | | O9 | — | — | — | 3.2 | — | — | — | — | — | — | — | — | | DGS4 | | | | | | | | | | | | | | O3 | 3.3 | 3.0 | — | — | — | — | — | — | — | — | — | — | | O5 | — | — | — | — | — | — | 3.1 | — | — | — | — | — | | O7 | — | — | — | — | 2.8 | 3.2 | — | 2.5 | — | — | — | — | | O8 | — | 3.3 | — | — | 2.9 | — | — | — | — | — | — | — |
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G4S: 4-O-sulfo-β-D-galactopyranose; 2DGS: 3,6-anhydro-D-galactose-2-sulfate.
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